Catalytic meta-selective C-H functionalization to construct quaternary carbon centres.
نویسندگان
چکیده
A catalytic meta-selective C-H functionalization of 2-phenylpyridines using a range of tertiary halides is described. The protocol is simple to perform and uses commercially available reagents to construct challenging quaternary carbon centres in a regioselective manner. Preliminary studies suggest the C-H functionalization proceeds through a radical process directed via a remote σ-activation.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 64 شماره
صفحات -
تاریخ انتشار 2015